الرئيسية › دليل الباحثين › Kevin Marsh
Kevin Marsh
الانتماء : Kenya Medical Research Institute · KEMRI-Wellcome Trust Research Programme
- 316منشورات (انتماء كيني)
الملف البحثي
لدى Kevin Marsh 316 منشور(ات) مفهرسة (2011–2025). تُنشر أعماله أساسًا في «PLoS ONE»، «BMC Medicine» و«Malaria Journal». أكثر مقالاته استشهادًا هو «Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing» (2012)، وقد استُشهد به 486 مرة. شارك في تأليف أعماله 12 باحثًا على الأقل، منهم باحثون من مؤسسات في المملكة المتحدة، أوغندا، تنزانيا، غانا.
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إنشاء ملفي المجاني إضافة منشوراتيالمنشورات (316)
- Plasmodium falciparum reticulocyte-binding homologues are targets of human inhibitory antibodies and play a role in immune evasion
- Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria
- Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response
- An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples
- Malaria protection due to sickle haemoglobin depends on parasite genotype
- Understanding the benefits and burdens associated with a malaria human infection study in Kenya: experiences of study volunteers and other stakeholders
- Identifying prognostic factors of severe metabolic acidosis and uraemia in African children with severe falciparum malaria: a secondary analysis of a randomized trial
- The remaining unknowns: a mixed methods study of the current and global health research priorities for COVID-19
- Funding and COVID-19 research priorities - are the research needs for Africa being met?
- Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
- Effect of ten-valent pneumococcal conjugate vaccine on invasive pneumococcal disease and nasopharyngeal carriage in Kenya: a longitudinal surveillance study
- IgM in human immunity to Plasmodium falciparum malaria
- Observational study: 27 years of severe malaria surveillance in Kilifi, Kenya
- Effect of 10-valent pneumococcal conjugate vaccine on the incidence of radiologically-confirmed pneumonia and clinically-defined pneumonia in Kenyan children: an interrupted time-series analysis
- Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort
- Gametocyte carriage in an era of changing malaria epidemiology: A 19-year analysis of a malaria longitudinal cohort
- A seven-year study on the effect of the pre-erythrocytic malaria vaccine candidate RTS,S/AS01E on blood stage immunity in young Kenyan children
- Few Plasmodium falciparum merozoite ligand and erythrocyte receptor pairs show evidence of balancing selection
- Exploring Plasmodium falciparum Var Gene Expression to Assess Host Selection Pressure on Parasites During Infancy
- Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
- KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization
- Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity
- Resistance to malaria through structural variation of red blood cell invasion receptors
- Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia
- Adaptation of Plasmodium falciparum to its transmission environment
- Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children
- Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure
- Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children
- Age, Spatial, and Temporal Variations in Hospital Admissions with Malaria in Kilifi County, Kenya: A 25-Year Longitudinal Observational Study
- Malaria hotspots defined by clinical malaria, asymptomatic carriage, PCR and vector numbers in a low transmission area on the Kenyan Coast
- Targets and Mechanisms Associated with Protection from Severe Plasmodium falciparum Malaria in Kenyan Children
- Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance
- Cord blood IgG and the risk of severe Plasmodium falciparum malaria in the first year of life
- A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies
- Mind the gap: jumping from vaccine licensure to routine use
- The effect of declining exposure on T cell-mediated immunity to Plasmodium falciparum – an epidemiological “natural experiment”
- Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection
- Prevalence, causes, and behavioral and emotional comorbidities of acute symptomatic seizures in Africa: A critical review
- Comparison of allele frequencies of Plasmodium falciparum merozoite antigens in malaria infections sampled in different years in a Kenyan population
- Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
- Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial
- Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria
- A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens
- Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults
- Malaria eradication and elimination: views on how to translate a vision into reality
- Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya
- Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies
- Genetic determinants of anti-malarial acquired immunity in a large multi-centre study
- Multiple clinical episodes of Plasmodium falciparum malaria in a low transmission intensity setting: exposure versus immunity
- Malaria and Age Variably but Critically Control Hepcidin Throughout Childhood in Kenya
- Identifying children with excess malaria episodes after adjusting for variation in exposure: identification from a longitudinal study using statistical count models
- Dynamics and role of antibodies to Plasmodium falciparum merozoite antigens in children living in two settings with differing malaria transmission intensity
- Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria
- Reappraisal of known malaria resistance loci in a large multicenter study
- New antigens for a multicomponent blood-stage malaria vaccine
- A micro-epidemiological analysis of febrile malaria in Coastal Kenya showing hotspots within hotspots
- Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection
- Plasmodium falciparum Malaria in Children Aged 0-2 Years: The Role of Foetal Haemoglobin and Maternal Antibodies to Two Asexual Malaria Vaccine Candidates (MSP3 and GLURP)
- Whole-Genome Scans Provide Evidence of Adaptive Evolution in Malawian Plasmodium falciparum Isolates
- Limited antigenic diversity of Plasmodium falciparumapical membrane antigen 1 supports the development of effective multi-allele vaccines
- Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya
- A Genome Wide Association Study of Plasmodium falciparum Susceptibility to 22 Antimalarial Drugs in Kenya
- Controlled human malaria infection in Kenyan adults: A safe model that could accelerate assessment of novel drugs and vaccines in malaria endemic populations
- Avidity of Anti-Circumsporozoite Antibodies following Vaccination with RTS,S/AS01E in Young Children
- Plasmodium falciparumantigenic variation: relationships between widespread endothelial activation, parasite PfEMP1 expression and severe malaria
- CD4+ T Cell Responses to the Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Mild Malaria
- Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure
- Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations
- A Library of Functional Recombinant Cell-surface and Secreted P. falciparum Merozoite Proteins
- A threshold concentration of anti-merozoite antibodies is required for protection from clinical episodes of malaria
- Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya
- Breadth of Anti-Merozoite Antibody Responses Is Associated With the Genetic Diversity of Asymptomatic Plasmodium falciparum Infections and Protection Against Clinical Malaria
- The Ratio of Monocytes to Lymphocytes in Peripheral Blood Correlates with Increased Susceptibility to Clinical Malaria in Kenyan Children
- Erythrocyte-Binding Antigens ofPlasmodium falciparumAre Targets of Human Inhibitory Antibodies and Function To Evade Naturally Acquired Immunity
- Plasmodium falciparum var Gene Expression Homogeneity as a Marker of the Host-Parasite Relationship under Different Levels of Naturally Acquired Immunity to Malaria
- Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data
- Antibodies to Polymorphic Invasion-Inhibitory and Non-Inhibitory Epitopes of Plasmodium falciparum Apical Membrane Antigen 1 in Human Malaria
- Phenotypic and Functional Profiling of CD4 T Cell Compartment in Distinct Populations of Healthy Adults with Different Antigenic Exposure
- Analysis of Antibodies to Newly Described Plasmodium falciparum Merozoite Antigens Supports MSPDBL2 as a Predicted Target of Naturally Acquired Immunity
- Plasmodium falciparum Infection Patterns Since Birth and Risk of Severe Malaria: A Nested Case-Control Study in Children on the Coast of Kenya
- Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
- Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)
- Chronic Exposure to Plasmodium falciparum Is Associated with Phenotypic Evidence of B and T Cell Exhaustion
- Targets of antibodies against Plasmodium falciparum–infected erythrocytes in malaria immunity
- Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya
- Prognostic Indicators of Life-Threatening Malaria Are Associated with Distinct Parasite Variant Antigen Profiles
- The Changing Limits and Incidence of Malaria in Africa
- Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children
- Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection
- Estimating Individual Exposure to Malaria Using Local Prevalence of Malaria Infection in the Field
- Lack of Avidity Maturation of Merozoite Antigen-Specific Antibodies with Increasing Exposure to Plasmodium falciparum amongst Children and Adults Exposed to Endemic Malaria in Kenya
- Genome Wide Adaptations of Plasmodium falciparum in Response to Lumefantrine Selective Drug Pressure
- T-Cell Responses to the DBLα-Tag, a Short Semi-Conserved Region of the Plasmodium falciparum Membrane Erythrocyte Protein 1
- Mortality in Sickle Cell Anemia in Africa: A Prospective Cohort Study in Tanzania
- Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study
- The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody
- Efficacy of RTS,S/AS01E malaria vaccine and exploratory analysis on anti-circumsporozoite antibody titres and protection in children aged 5–17 months in Kenya and Tanzania: a randomised controlled trial
- Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast
- Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome
- A Molecular Epidemiological Study of var Gene Diversity to Characterize the Reservoir of Plasmodium falciparum in Humans in Africa
مجلات النشر
- PLoS ONE × 16
- BMC Medicine × 8
- Malaria Journal × 7
- Nature Communications × 5
- Wellcome Open Research × 4
- Frontiers in Immunology × 3
المنشورات حسب السنة
- 20251
- 20222
- 20214
- 20202
- 201910
- 20182
- 20176
- 201612
- 201513
- 201414
التعاون العلمي
المؤسسات الشريكة : University of Oxford · Wellcome Trust · John Radcliffe Hospital · London School of Hygiene & Tropical Medicine · University College London
بلدان المؤلفين المشاركين : المملكة المتحدة · أوغندا · تنزانيا · غانا
المؤلفون المشاركون
- Thomas Neil Williams
- Philip Bejon
- Norbert M. Peshu
- Charles R. J. C. Newton
- Robert William Snow
- Brett S Lowe
- Faith H. A. Osier
- Peter C. Bull
- Tabitha Mwangi
- Greg Fegan
- James Alexander Berkley
- Patricia Njuguna
البيانات البيبليوغرافية مصدرها OpenAlex (قاعدة مفتوحة).
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