Home › Researcher directory › Moncef Msaddek
Moncef Msaddek
Affiliation : University of Monastir
- 102Publications (affiliation in Tunisia)
- 165Total publications
- 1144Citations
- 16h-index
Research profile
Moncef Msaddek has 102 indexed publications (1998–2026). Their work appears mainly in “ChemInform”, “Journal of Molecular Structure” and “Comptes Rendus Chimie”. Their most cited article, “1,3-Dipolar cycloaddition reactions on carbohydrate-based templates: synthesis of spiro-isoxazolines and 1,2,4-oxadiazoles as glycogen phosp” (2006), has been cited 85 times. 8 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in France, Saudi Arabia, Canada.
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Create my free profile Add my publicationsResearch areas
- Crystal structures of chemical compounds
- Crystallography and molecular interactions
- Crystal Structures and Properties
- Organic Chemistry Cycloaddition Reactions
- Asymmetric Synthesis and Catalysis
Publications (102)
- Integrative design and optimization of bioactive schiff bases using computational intelligence and molecular modeling
- Dual-function advanced magnetic bacterial cellulose materials: From enhanced adsorption phenomena to an unprecedented circular green catalytic strategy
- Cycloaddition des Arylnitriloxydes sur quelques énones, Synthèse d’un Antioxydant de type Hydroxy Propanitrile
- Taguchi method and neural network for efficient β‐ketoenamine synthesis in deionized water
- Optimizing synthesis and catalytic performance of novel β-keto-enamine complexes of Ni (II) using BBD design and PSO-ANN
- A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes
- Novel Pyridyl Macrocyclic Triarylmethanes: Synthesis by Ring-closing Metathesis and Chemical Analysis
- Front Cover: A Promising Approach to Target Colorectal Cancer Using Hybrid Triarylmethanes (ChemMedChem 21/2024)
- Multiple linear regression and artificial neural networks for highly selective cationic β‐diimine‐methallyl nickel (II) catalyst for styrene dimerization reaction to 1,3‐diphenyl‐1‐butene
- Synthesis of new 1,2,3-triazole linked benzimidazolidinone: Single crystal X-ray structure, biological activities evaluation and molecular docking studies
- Design and synthesis of new N-substituted benzimidazolidinone as predicted human BRD4 and human chymase inhibitors via molecular docking studies
- Chemoselective chlorination of 1,5-benzodiazepin-2-one derivatives by activated DMSO
- Colorectal anticancer activity of a novel class of triazolic triarylmethane derivatives
- Novel isoxazole linked 1,5- benzodiazepine derivatives: Design, synthesis, molecular docking and antimicrobial evaluation
- Synthesis and structure of polycyclic 1,2,3-triazolylmethyl-benzimidazole derivatives — Experimental and computational quantum chemical studies
- Regioselective One-Pot Synthesis, Biological Activity and Molecular Docking Studies of Novel Conjugates N-(p-Aryltriazolyl)-1,5-benzodiazepin-2-ones as Potent Antibacterial and Antifungal Agents
- Novel Set of Diarylmethanes to Target Colorectal Cancer: Synthesis, In Vitro and In Silico Studies
- β-Diimine-methallyl nickel complexes in ionic liquid: A biphasic green system for the high selective styrene dimerization
- Microwave-assisted synthesis of (3,5-disubstituted isoxazole)-linked benzimidazolone derivatives: DFT calculations and biological activities
- Design, synthesis and photoluminescent studies of new 1,5-benzodiazepines derivatives: Towards new ESIPT compounds
- Synthesis of New Chiral Triazoles Linked 1,5‐Benzodiazepine Conjugates via Copper‐Catalyzed 1,3‐Dipolar Cycloaddition Reaction
- Structural and computational analyses of a 2-propanolammonium-chlorocadmate(II) assembly: Pivotal role of hydrogen bonding and H—H interactions
- Neutral nickel(II) complex bearing hemilabile N,S-donor ligands – structural, Hirshfeld surfaces and DFT studies
- Crystallographic and first‐principles density functional theory study on the structure, noncovalent interactions, and chemical reactivity of 1,5‐benzodiazepin‐2‐ones derivatives
- Design and microwave-assisted synthesis of dimers of 1,5-benzodiazepine-1,2,3-triazole hybrids bearing alkyl/aryl spacers and their biological assessment
- Cationic allyl nickel complexes containing N,O-donor labile ligands: Synthesis and molecular characterisation
- Unprecedented Synthesis of 4‐Ylidene (3 S )‐3‐hydroxy‐1‐aryl (alkyl)‐pyrrolidine‐2,5‐diones Based on 1,3‐Dipolar Cycloaddition of a Sugar‐derived Nitrone to N ‐Substituted Maleimides
- Synthesis and structural studies of hexafluorophosphate-based organic salts: A combined experimental and computational analysis
- Synthesis of some new diarylmethanes by McMurry coupling reaction: characterization and antibacterial activity
- Crystal Structure of Cationic η3-Methallylpalladium Complexes Bearing Aliphatic Iminopyridine Ligands
- Design, synthesis, molecular properties and in vitro antioxidant and antibacterial potential of novel enantiopure isoxazolidine derivatives
- Cationic allylnickel(II) complexes bearing labile N,S-donor ligands: Synthesis, characterization and crystal structure
- Highly diastereoselective synthesis of rigid 3-enamino-1,5-benzodiazepines
- Synthesis of Novel Pyrazole–sucrose Derivatives by 1,3‐dipolar Cycloaddition
- Synthesis, characterization, and crystal structure of novel bulky phenyl‐bridged α‐diimine binucleating ligands
- Utilisation of click chemistry in medicinal chemistry. Applications to the synthesis of new bioactive triarylmethanes.
- New Synthesized Derivatives from N-Substituted-4-Oxo-[1] Benzopyrano [4,3-c] Pyrazole Influenced Proliferation, Viability, Spreading and Invasion of Human Liver Tumor Cells
- Stereoselective synthesis of enantiopure N-substituted pyrrolidin-2,5-dione derivatives by 1,3-dipolar cycloaddition and assessment of their in vitro antioxidant and antibacterial activities
- Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones
- Regioselective synthesis of o-triazolyl-1,5-benzodiazepin-2-ones and o-isoxazolyl-1,5-benzodiazepin-2-ones via copper-catalyzed 1,3-dipolar cycloaddition reactions
- Synthesis of carbohydrate-substituted isoxazoles and evaluation of their antitubercular activity
- Correction: Metal-free oxidative ring contraction of benzodiazepinones: an entry to quinoxalinones
- Corrigendum to “Direct oxidation of Δ2-isoxazolines synthesis by metal ion-mediated diastereoface-selective 1,3-dipolar cycloaddition with “activated” DMSO” [Arab. J. Chem. 10(Suppl. 1) (2017) S800–S803]
- Unprecedented stereoselective synthesis of 3-methylisoxazolidine-5-aryl-1,2,4-oxadiazoles via 1,3-dipolar cycloaddition and study of their in vitro antioxidant activity
- 1,5-Benzodiazepin-2-ones: Investigation of a Family of Photoluminescent Materials
- Solution and solid-state fluorescence of 2-(2′-hydroxyphenyl)-1,5-benzodiazepin-2-one (HBD) borate complexes
- Synthesis of Some Isoxazolidine and Isoxazoline Derivatives Using Nitrone-Derived (‒)-Menthone via 1,3-Dipolar Cycloaddition with Alkenes, Alkynes and Cycloalkenes
- A stereoselective method for the synthesis of enantiopure 3-substituted 4-hydroxyproline derivatives via 1,3-dipolar cycloadditions
- One-pot synthesis of new triazole-sucrose derivatives via click chemistry and evaluation of their antitubercular activity
- Novel cationic dinuclear η3-methallylpalladium complexes containing N,N′-donor bridging ligands: Synthesis, characterization and crystal structure
- Unprecedented 3- O -methyl-3- C -trifluoromethyl- d -ribono- (and l -lyxono)-γ-lactones synthesized by nucleophilic trifluoromethylation of d -hexose-derived cyclic ketones
- Crystal structure of (1S,2S,2′R,3a′S,5R)-2′-[(5-bromo-1H-indol-3-yl)methyl]-2-isopropyl-5,5′-dimethyldihydro-2′H-spiro[cyclohexane-1,6′-imidazo[1,5-b]isoxazol]-4′(5′H)-one
- Crystal structure of 5-chloromethyl-N-methyl-4-[(4-phenyl-1,2,3-triazol-1-yl)methyl]isoxazolidine-3-carboxamide
- Crystal structure of 2-isopropyl-5,7′-dimethyl-1′,3′,3a',6′,8a',8b'-hexahydrospiro[cyclohexane-1,6′-furo[3,4-d]imidazo[1,5-b]isoxazol]-8′(7′H)-one
- cristal structure of 5-chloro-methyl-N-methyl-4-[(4-phenyl-1.2.3-triazol-1-yl)]isoxazolidine-3-carboxamide
- Copper Nanoparticles Cycloaddition of Terminal Acetylenes with Carbohydrate Azide
- Unexpected synthesis of aziridines under Cu(I) catalyzed Kinugasa conditions assisted by microwave irradiation
- Synthesis, characterization and crystal structure of cationic bis(pyridinylimine)cobalt(II) complexes
- ChemInform Abstract: Stereoselective Synthesis of Enantiopure Cycloalkylglycines by 1,3‐Dipolar Cycloaddition of a Chiral Nitrone to Cycloalkenes.
- Stereoselective Synthesis of Enantiopure Cycloalkylglycines by 1,3‐Dipolar Cycloaddition of a Chiral Nitrone to Cycloalkenes
- A Cycloaddition–Cyclization Combined Approach to Enantiopure 3‐Glycinyl‐4‐hydroxypyrrolidines and 3‐Substituted 4‐Hydroxyprolines
- Novel cationic η3-methallyl palladium complexes bearing pyridinyl-imine ligands: Synthesis, characterization and X-ray study
- Synthesis of New Spirocyclopropane and Oxadiazole Products
- Synthesis of novel O-alkylbenzochromeno-1,5-benzodiazepinones. Study of the N–H····N and CO····HN hydrogen bonding interactions with 2-aminopyridines
- Stereoselective synthesis of 1,2,3-triazolyl-functionalized isoxazolidines, via two consecutive 1,3-dipolar cycloadditions, as precursors of unnatural amino acids
- A Facile One Pot Synthesis of Substituted Pyrazole Derivatives
- ChemInform Abstract: Synthesis of New Pyrazolines and Their Biological Evaluation as Antimicrobial Agents.
- ChemInform Abstract: A Facile One Pot Synthesis of Substituted Pyrazole Derivatives.
- ChemInform Abstract: Chemo‐ and Regioselective 1,3‐Dipolar Cycloaddition of 2‐Diazopropane over 1,4‐Benzoquinone: Synthesis of New Pyrazoloquinones.
- First application of chlorophyll-a as biomordant: sonicator dyeing of wool with betanin dye
- 1,3-Dipolar cycloaddition of a chiral nitrone to (E)-1,4-dichloro-2-butene: a new efficient synthesis of (2S,3S,4R)-4-hydroxyisoleucine
- Synthesis and reactivity of N-sugar-maleimides: an access to novel highly substituted enantiopure pyrazolines
- A facile and efficient ultrasound-assisted stereospecific synthesis of novel bicyclo-cyclopropanes
- Chemoselectivity of the 1,3-Dipolar Cycloaddition of Some Diazoalkanes with 1,5-Benzodiazepine Derivatives
- Synthesis of New Pyrazolines and their Biological Evaluation as Antimicrobial Agents
- An unexpected transformation by reduction of isoxazolines
- Chemo- and Regioselective 1,3-Dipolar Cycloaddition of 2-Diazopropane over 1,4-Benzoquinone: Synthesis of New Pyrazoloquinones
- Direct oxidation of Δ 2 -isoxazolines synthesis by metal ion-mediated diastereoface-selective 1,3-dipolar cycloaddition with “activated” DMSO
- ChemInform Abstract: Synthesis and Chemistry of New Spiro‐Δ1‐pyrazoline.
- ChemInform Abstract: Chemoselectivity of the 1,3‐Dipolar Cycloaddition of Some Diazoalkanes with 1,5‐Benzodiazepine Derivatives.
- ChemInform Abstract: Study of the Regio‐ and Stereoselectivity of [3 + 2] Cycloaddition of Nitrile Oxides to Various Racemic 3‐Acyloxy and 3‐Hydroxybut‐1‐enes.
- Cycloaddition of a chiral nitrone to allylic motifs: an access to enantiopure sugar-based amino acids displaying a stable glycosidic bond and to 4(S)-4-hydroxy-l-ornithine
- 1,3-dipolar cycloadditions of arylnitrile oxides and 2-diazopropane with 5-hydroxy-3-methyl-1,5-dihydropyrrol-2-one derivatives
- Synthesis and chemistry of new spiro‐Δ1‐pyrazoline
- The Swern Oxidation: First example of direct oxidation of 2-pyrazolines with “activated” DMSO
- Synthesis and chemistry of pyrazolines derived from diphenyldiazomethane
- Analogues of insulin secretagogue (2S,3R,4S)-4-hydroxyisoleucine: synthesis by 1,3-dipolar cycloaddition reactions of chiral nitrones to alkenes
- Halolactonization of g-Acetylenic Acids: Synthesis of Novel Spiroisoindole Halobutyrolactones
- ChemInform Abstract: Synthesis and Photolysis of Hexahydropyrrolo[3,4‐c]pyrazole Derivatives.
- Regio- and Stereoselectivity in 1,3-dipolar Cycloaddition Reaction of 2-diazopropane with Benzylidene-N-arylsuccinimide and Benzylidene-N-arylmethylsuccinimide Derivatives: Synthesis of Gem-dimethylcyclopropane
- Synthesis and Photolysis of Hexahydropyrrolo[3,4- c ]pyrazole derivatives
- Regio‐ and Stereoselectivity in 1,3‐Dipolar Cycloaddition Reaction of 2‐Diazopropane with Benzylidene‐N‐arylsuccinimide and Benzylidene‐N‐arylmethylsuccinimide Derivatives: Synthesis of gem‐Dimethylcyclopropane.
- 1,3-Dipolar cycloaddition reactions on carbohydrate-based templates: synthesis of spiro-isoxazolines and 1,2,4-oxadiazoles as glycogen phosphorylase inhibitors
- In Search of Glycogen Phosphorylase Inhibitors: 5‐Substituted 3‐C‐Glucopyranosyl‐1,2,4‐oxadiazoles from β‐ D ‐Glucopyranosyl Cyanides upon Cyclization of O‐Acylamidoxime Intermediates
- Cycloadditions of Chiral Nitrones to Racemic 3-Substituted Butenes: A Direct Access with Kinetic Resolution to Enantiopure Dihydroxylated Amino Acids
- SYNTHESIS AND EVOLUTION OF NEW ISOXAZOLO-1,4-QUINONES OF BIOLOGIC INTEREST
- Cycloadditions of chiral nitrones to racemic 3-substituted butenes: A direct access with kinetic resolution to enantiopure dihydroxylated amino acids
- Unexpected Rearrangements of Bicyclic Pyrazolines Derived from 6,6-Diphenylpentafulvene
- Reaction of 2-Benzoyl-1,2-dihydroisoquinoline-1-carbonitrile Tetrafluoroborate with (Z)-2-Arylidene-3(2H)-benzofuranones – Access to Chromenopyrrole Derivatives
- ChemInform Abstract: Regio‐ and Diastereochemistry of the [4 + 2] Cycloaddition of 2‐Benzoyl‐1,2‐dihydroisoquinoline‐1‐carbonitrile Tetrafluoroborate with (Z)‐ and (E)‐3‐Arylidene‐2‐(3H)‐benzofuranones.
Publication venues
- ChemInform × 10
- Journal of Molecular Structure × 9
- Comptes Rendus Chimie × 8
- European Journal of Organic Chemistry × 5
- Journal of Chemical Research × 5
- Arabian Journal of Chemistry × 4
Publications per year
- 20261
- 20252
- 20245
- 20235
- 20225
- 20213
- 20202
- 20197
- 20187
- 20176
Collaborations
Partner institutions : University of Kairouan · Centre National de la Recherche Scientifique · Conservatoire National des Arts et Métiers · University of Sousse · Lyon 1 Université
Co-authors’ countries : France · Saudi Arabia · Canada
Co-authors
- Naoufel Ben Hamadi
- Kaïss Aouadi
- Hasan Mtiraoui
- Ali Mechria
- Rafik Gharbi
- Asma Nsira
- Ameni Hadj Mohamed
- Taha Guerfel
- Melek Hajji
- Jihed Brahmi
- Heithem Abda
- Siwar Ghannay
Bibliographic data from OpenAlex (open database).
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