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Pascal Bonnet

Affiliation : Université d'Orléans · Centre National de la Recherche Scientifique · Institut de Chimie Organique et Analytique

• 6Publications (affiliation in France)
• 163Total publications
• 2681Citations
• 30h-index

ORCIDOpenAlex

Research profile

Pascal Bonnet has 6 indexed publications (2013–2021). Their work appears mainly in “European Journal of Medicinal Chemistry”, “Advanced Synthesis & Catalysis” and “Journal of Medicinal Chemistry”. Their most cited article, “Design, Synthesis, and Biological Activity of Pyridopyrimidine Scaffolds as Novel PI3K/mTOR Dual Inhibitors” (2013), has been cited 86 times. 2 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in Morocco.

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Research areas

• Computational Drug Discovery Methods
• Synthesis and biological activity
• Protein Kinase Regulation and GTPase Signaling
• Protein Structure and Dynamics
• Synthesis and Characterization of Heterocyclic Compounds

Publications (6)

• Palladium‐Catalyzed Regioselective C−H Arylation of 4‐Azaindazole at C3, C5 and C7 Positions
  2021 · Advanced Synthesis & Catalysis · cited 12 times
• Front Cover Picture: Palladium‐Catalyzed Regioselective C−H Arylation of 4‐Azaindazole at C3, C5 and C7 Positions (Adv. Synth. Catal. 16/2021)
  2021 · Advanced Synthesis & Catalysis
• Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors
  2016 · European Journal of Medicinal Chemistry · cited 19 times
• Advances in tetrahydropyrido[1,2- a ]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors
  2015 · European Journal of Medicinal Chemistry · cited 35 times
• Synthesis and optimization of an original V-shaped collection of 4-7-disubstituted Pyrido[3,2-d]pyrimidines as CDK5 and DYRK1A inhibitors
  2014 · European Journal of Medicinal Chemistry · cited 43 times
• Design, Synthesis, and Biological Activity of Pyridopyrimidine Scaffolds as Novel PI3K/mTOR Dual Inhibitors
  2013 · Journal of Medicinal Chemistry · cited 86 times

Publication venues

• European Journal of Medicinal Chemistry × 3
• Advanced Synthesis & Catalysis × 2
• Journal of Medicinal Chemistry × 1

Publications per year

• 20212
• 20161
• 20151
• 20141
• 20131

Collaborations

Partner institutions : Inserm · Université de Rennes · Station Biologique de Roscoff · Euro-Mediterranean University of Fes · Structure Fédérative de Recherche en Biologie et Santé de Rennes

Co-authors’ countries : Morocco

Co-authors

• Stéphane Bourg
• Gérald Guillaumet
• Sylvain Routier
• Olivier Lozach
• Laurent Meijer
• Christiane Guguen‐Guillouzo
• Rémy Le Guével
• Aziz Ouach
• Yves Troin
• Samia Aci‐Sèche
• Franck Suzenet
• Otmane Bourzikat

Bibliographic data from OpenAlex (open database).