Home › Researcher directory › Houcemeddine Othman
Houcemeddine Othman
Affiliation : Hôpital Farhat Hached · University of Sousse
- 44Publications (affiliation in Tunisia)
- 93Total publications
- 1263Citations
- 19h-index
Research profile
Houcemeddine Othman has 44 indexed publications (2012–2026). Their work appears mainly in “International Journal of Biological Macromolecules”, “Toxicon” and “Research Square”. Their most cited article, “The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells” (2019), has been cited 133 times. 13 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in South Africa, France, Spain, United States.
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Create my free profile Add my publicationsResearch areas
- Venomous Animal Envenomation and Studies
- Healthcare and Venom Research
- SARS-CoV-2 and COVID-19 Research
- Pharmacogenetics and Drug Metabolism
- vaccines and immunoinformatics approaches
Publications (44)
- Antibacterial activity of peptide derivatives of dermaseptins against multidrug-resistant Klebsiella pneumoniae and Staphylococcus epidermis
- Towards globally equitable bioinformatics adoption
- Socio-genomics of intellectual disability in African populations: top research-producing countries
- A novel mRNA-based multi-epitope vaccine for rabies virus computationally designed via reverse vaccinology and immunoinformatics
- Characterization of NAT , GST , and CYP2E1 Genetic Variation in Sub‐Saharan African Populations: Implications for Treatment of Tuberculosis and Other Diseases
- Utility of regional STR marker variations in Tunisian and sub-Saharan populations: insights into forensic and population genetics
- Report of a missense TJP2 variant associated to PFIC4 with a pronounced phenotypic variability: Focus on the structural effects on the protein level
- The AlphaFold educational summit provides insights into advancing global equity in computational structural biology
- Is Tunisia ready for precision medicine? Challenges of medical genomics within a LMIC healthcare system
- Overexpression of WT1 in all molecular subtypes of breast cancer and its impact on survival: exploring oncogenic and tumor suppressor roles of distinct WT1 isoforms
- Honey-based therapeutics: a comprehensive review of anticancer, antioxidant, and prognostic impacts in breast cancer treatment
- In vitro Antileishmanial Activity and In silico Molecular Modeling Studies of Novel Analogs of Dermaseptins S4 and B2
- Genetic Insights Into Epidermolysis Bullosa: Identification of Novel Variants in Tunisian Patients
- The E6 gene polymorphism of Human papillomavirus 16 in relation to the risk of cervical cancer in Tunisian women
- PHINDaccess Hackathons for COVID‐19 and Host‐Pathogen Interaction: Lessons Learned and Recommendations for Low‐ and Middle‐Income Countries
- Characterizing the Combined Effects of Cytochrome P450 Missense Variation within Star Allele Definitions
- SARS-CoV-2 Spike Protein Unlikely to Bind to Integrins via the Arg-Gly-Asp (RGD) Motif of the Receptor Binding Domain: Evidence From Structural Analysis and Microscale Accelerated Molecular Dynamics
- AaTs-1: A Tetrapeptide from Androctonus australis Scorpion Venom, Inhibiting U87 Glioblastoma Cells Proliferation by p53 and FPRL-1 Up-Regulations
- In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
- In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of possible putative protective effect
- In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of possible putative protective effect
- The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
- Anti-tumoral effect of scorpion peptides: Emerging new cellular targets and signaling pathways
- AaHIV a sodium channel scorpion toxin inhibits the proliferation of DU145 prostate cancer cells
- N-glycosylation and homodimeric folding significantly enhance the immunoreactivity of Mycobacterium tuberculosis virulence factor CFP32 when produced in the yeast Pichia pastoris
- Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells
- Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides
- Targeting α1 inserted domain (I) of α1β1 integrin by Lebetin 2 from M. lebetina transmediterranea venom decreased tumorigenesis and angiogenesis
- RK, the first scorpion peptide with dual disintegrin activity on α1β1 and αvβ3 integrins
- Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin
- Functional and Structural Characterization of a Thermostable Phospholipase A2 from a Sparidae Fish (Diplodus annularis)
- Efficient heterologous expression, functional characterization and molecular modeling of annular seabream digestive phospholipase A2
- Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
- In Silico prediction of the molecular basis of ClTx and AaCTx interaction with matrix metalloproteinase-2 (MMP-2) to inhibit glioma cell invasion
- Biochemical and monolayer characterization of Tunisian snake venom phospholipases
- Insights into Ionizing-Radiation-Resistant Bacteria S-Layer Proteins and Nanobiotechnology for Bioremediation of Hazardous and Radioactive Waste
- Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kD a are behind the discrepancy around its biological functions
- Characterization of Kbot21 Reveals Novel Side Chain Interactions of Scorpion Toxins Inhibiting Voltage-Gated Potassium Channels
- A thermoactive l-amino acid oxidase from Cerastes cerastes snake venom: Purification, biochemical and molecular characterization
- The galactolipase activity of Fusarium solani (phospho)lipase
- AaTX1, from Androctonus australis scorpion venom: Purification, synthesis and characterization in dopaminergic neurons
- 24. Purification, biochemical and molecular characterization of an L-amino acid oxidase from Cerastes cerastes snake venom
- 30. Structure function relationship study of Kbot21, a new potassium channel blocker from the Tunisian scorpion Buthus occitanus tunetanus
- PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells
Publication venues
- International Journal of Biological Macromolecules × 4
- Toxicon × 4
- Research Square × 3
- Journal of Community Genetics × 2
- Scientific Reports × 2
- Biochemical and Biophysical Research Communications × 2
Publications per year
- 20263
- 20255
- 20245
- 20233
- 20221
- 20212
- 20202
- 20194
- 20184
- 20173
Collaborations
Partner institutions : Institut Pasteur de Tunis · Tunis El Manar University · Tunis University · University of Sfax · Faculté de médecine de Tunis
Co-authors’ countries : South Africa · France · Spain · United States
Co-authors
- Najet Srairi‐Abid
- Mohamed El Ayeb
- Naziha Marrakchi
- Khadija Essafi‐Benkhadir
- Zaineb Abdelkafi-Koubaa
- Kaïs Ghedira
- Youssef Gargouri
- Maram Morjen
- Oussema Khamessi
- Jed Jebali
- Haïfa El Mabrouk
- Meriam Haoues
Bibliographic data from OpenAlex (open database).
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