Home › Researcher directory › Imen Ayed‐Boussema
Imen Ayed‐Boussema
Affiliation : University of Monastir · University of Gafsa
- 42Publications (affiliation in Tunisia)
- 43Total publications
- 1218Citations
- 18h-index
Research profile
Imen Ayed‐Boussema has 42 indexed publications (2004–2026). Their work appears mainly in “Drug and Chemical Toxicology”, “NeuroToxicology” and “Toxicology Letters”. Their most cited article, “The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: Oxidative DNA damage, gluthatione depletion and stress protei” (2007), has been cited 175 times. 7 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in United Kingdom.
Is this you? Get your research seen
Create your free DzCademia profile and add your articles: they will show up more easily on Google and in AI assistants like ChatGPT, so more people can read and cite your work.
Create my free profile Add my publicationsResearch areas
- Carcinogens and Genotoxicity Assessment
- Mycotoxins in Agriculture and Food
- Pesticide Exposure and Toxicity
- Chemotherapy-induced organ toxicity mitigation
- Erythropoietin and Anemia Treatment
Publications (42)
- Myricetin mitigates trifloxystrobin neurotoxicity by modulating the integrated stress response pathway and antioxidant defense in sH-SY5Y cells
- Trifloxystrobin-Induced Neurotoxicity in Wistar Rats: Biomarkers of Oxidative Stress, Cholinergic Dysfunction, and DNA Damage
- Mitochondria-driven oxidative stress mediates cyproconazole-induced genotoxicity, caspase-dependent apoptosis, and glial neuroinflammation in human neuronal and glial cell lines
- Mitochondrial complex I and II inhibiting pesticides activate DELE1-HRI integrated stress signaling but engage distinct cell death programs in human neuronal cells
- Cyproconazole‐Induced Systemic Neuro‐Immunotoxicity: An Integrated In Vivo and In Silico Study of Oxidative Stress, NLRP3‐Related Inflammatory Signaling, and Cholinergic Disruption
- In primary human lymphocytes, the triazole fungicide cyproconazole impairs regulatory B cell interleukin-10 expression and induces T cell senescence
- Subchronic exposure to fenpyroximate causes multiorgan toxicity in Wistar rats by disrupting lipid profile, inducing oxidative stress and DNA damage
- Oxidative stress-mediated mitochondrial apoptosis induced by the acaricide, fenpyroximate, on cultured human colon cancer HCT 116 cells
- Epoxiconazole caused oxidative stress related DNA damage and apoptosis in PC12 rat Pheochromocytoma
- Genotoxic damage and apoptosis in rat glioma (F98) cell line following exposure to bromuconazole
- Fenpyroximate induced cytotoxicity and genotoxicity in Wistar rat brain and in human neuroblastoma (SH-SY5Y) cells: Involvement of oxidative stress and apoptosis
- Evaluation of hepatotoxicity and nephrotoxicity induced by fenpyroximate in subchronic-orally exposed Wistar rats
- Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process
- The mycotoxin zearalenone enhances cell proliferation, colony formation and promotes cell migration in the human colon carcinoma cell line HCT116
- Ochratoxin A and T‐2 Toxin Induce Clonogenicity and Cell Migration in Human Colon Carcinoma and Fetal Lung Fibroblast Cell Lines
- Effect of recombinant human erythropoietin on mitomycin C-induced oxidative stress and genotoxicity in rat kidney and heart tissues
- Protective effect of Mycophenolate mofetil on Tacrolimus-induced liver injury in rat
- Role of recombinant human erythropoietin against mitomycin C-induced cardiac, hepatic and renal dysfunction in Wistar rats
- Role of recombinant human erythropoietin in mitomycin C-induced genotoxicity: Analysis of DNA fragmentation, chromosome aberrations and micronuclei in rat bone-marrow cells
- Antioxidant and antigenotoxic role of recombinant human erythropoeitin against alkylating agents: Cisplatin and mitomycin C in cultured Vero cells
- Induction of DNA fragmentation, chromosome aberrations and micronuclei by cisplatin in rat bone-marrow cells: Protective effect of recombinant human erythropoietin
- The protective effect of recombinant human erythropoietin against cisplatin-induced renal and hepatic dysfunctions in Wistar rats
- Effect of Aflatoxin B1 on Nuclear Receptors PXR, CAR, and AhR and Their Target Cytochromes P450 mRNA Expression in Primary Cultures of Human Hepatocytes
- Antioxidative and antigenotoxic effect of vitamin E against patulin cytotoxicity and genotoxicity in HepG2 cells
- In vitro and in vivo induction of chromosome aberrations by alpha- and beta-zearalenols: Comparison with zearalenone
- Genotoxicity Evaluation of Dimethoate to Experimental Mice by Micronucleus, Chromosome Aberration Tests, and Comet Assay
- Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors
- Genotoxicity associated with oxidative damage in the liver and kidney of mice exposed to dimethoate subchronic intoxication
- Protective effect of erythropoietin against cisplatin-induced nephrotoxicity in rats: antigenotoxic and antiapoptotic effect
- Protective effect of recombinant human erythropoeitin against cisplatin cytotoxicity and genotoxicity in cultured Vero cells
- The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes
- Recombinant human erythropoietin prevents cisplatin-induced genotoxicity in rat liver and heart tissues via an antioxidant process
- Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes
- Effects of the mycotoxins aflatoxin B1, zearalenone and ochratoxine A on nuclear receptors PXR, CAR and AhR expression and corresponding CYP 450 in primary cultured human hepatocytes
- Individual and combined effects of ochratoxin A and citrinin on viability and DNA fragmentation in cultured Vero cells and on chromosome aberrations in mice bone marrow cells
- The mycotoxin Zearalenone induces apoptosis in human hepatocytes (HepG2) via p53-dependent mitochondrial signaling pathway
- The antigenotoxic activities of cactus (Opuntia ficus-indica) cladodes against the mycotoxin zearalenone in Balb/c mice: Prevention of micronuclei, chromosome aberrations and DNA fragmentation
- Cactus (Opuntia ficus-indica) cladodes prevent oxidative and DNA damage induced by the mycotoxin zearalenone in Balb/c mice
- The role of oxidative stress in zearalenone-mediated toxicity in Hep G2 cells: Oxidative DNA damage, gluthatione depletion and stress proteins induction
- Toxicities induced in cultured cells exposed to zearalenone: Apoptosis or mutagenesis?
- Heat shock proteins (Hsp 70) response is not systematic to cell stress
- Zearalenone induces chromosome aberrations in mouse bone marrow: preventive effect of 17β-estradiol, progesterone and Vitamin E
Publication venues
- Drug and Chemical Toxicology × 5
- NeuroToxicology × 4
- Toxicology Letters × 4
- Mutation Research/Genetic Toxicology and Environmental Mutagenesis × 4
- Biomarkers × 3
- Human & Experimental Toxicology × 3
Publications per year
- 20266
- 20241
- 20231
- 20225
- 20162
- 20152
- 20141
- 20132
- 20122
- 201110
Collaborations
Partner institutions : Hôpital Sahloul · Hôpital Farhat Hached · Hospital Fatuma Bourguiba Monastir · University College London
Co-authors’ countries : United Kingdom
Co-authors
- Hassen Bacha
- Karima Rjiba-Touati
- Wafa Hassen
- Salwa Abid
- Karima Rjiba
- Hiba Hamdi
- Hanen Chaabani
- Salwa Abid‐Essefi
- Asma M’nassri
- Anis Belarbia
- Y. Guedri
- Abdelatif Achour
Bibliographic data from OpenAlex (open database).
Why choose Dzcademia?
Profiles, articles and conference contributions: give your research a structured public presence. Integrated metadata help search engines and AI assistants identify your work and understand its references.
Comment with Google
Sign in with Google to comment directly on this page.