Home › Researcher directory › Makram Essafi
Makram Essafi
Affiliation : Institut Pasteur de Tunis · Tunis El Manar University
- 26Publications (affiliation in Tunisia)
- 41Total publications
- 1458Citations
- 20h-index
Research profile
Makram Essafi has 26 indexed publications (2002–2026). Their work appears mainly in “Frontiers in Immunology”, “International Journal of Molecular Sciences” and “RSC Advances”. Their most cited article, “Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequentl” (2018), has been cited 141 times. 4 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in France, China, United States, Saudi Arabia.
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Create my free profile Add my publicationsResearch areas
- Tuberculosis Research and Epidemiology
- Medicinal Plant Research
- Phytochemicals and Antioxidant Activities
- FOXO transcription factor regulation
- Pomegranate: compositions and health benefits
Publications (26)
- Forkhead box O3 transcription factor fine-tunes IL-6 expression in mycobacteria-infected macrophages
- Leishmania infantum eukaryotic initiation factor 4A modulates in vitro functional activity of human neutrophils
- Deciphering the Mechanisms Underlying the Antitumor Effects of Eucalyptus Essential Oil and Its Component 3-Cyclohexene-1-Methanol Against Human Colon Cancer Cells
- Detection of SARS-CoV-2 N protein using AgNPs-modified aligned silicon nanowires BioSERS chip
- Essential oil and its nanoemulsion of Eucalyptus cladocalyx : chemical characterization, antioxidant, anti-inflammatory and anticancer activities
- Editorial: Repurposed Drugs as Immune-Modulators to Combat Infectious Diseases
- Multiplexed Magnetofluorescent Bioplatform for the Sensitive Detection of SARS-CoV-2 Viral RNA without Nucleic Acid Amplification
- Co-Administration of Anticancer Candidate MK-2206 Enhances the Efficacy of BCG Vaccine Against Mycobacterium tuberculosis in Mice and Guinea Pigs
- The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
- FOXO3 Transcription Factor Regulates IL-10 Expression in Mycobacteria-Infected Macrophages, Tuning Their Polarization and the Subsequent Adaptive Immune Response
- NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G
- Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 Phenotype
- An advanced intelligent ELISA test for bovine tuberculosis diagnosis
- Ultrasensitive detection of hazardous reactive oxygen species using flexible organic transistors with polyphenol-embedded conjugated polymer sensing layers
- Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
- Detection of ESAT-6 by a label free miniature immuno-electrochemical biosensor as a diagnostic tool for tuberculosis
- Allium RoseumL. Extract Exerts Potent Suppressive Activities on Chronic Myeloid Leukemia K562 Cell Viability Through the Inhibition of BCR-ABL, PI3K/Akt, and ERK1/2Pathways and the Abrogation of VEGF Secretion
- Quince peel polyphenolic extract blocks human colon adenocarcinoma LS174 cell growth and potentiates 5-fluorouracil efficacy
- Two distinct conformational states of Mycobacterium tuberculosis virulent factor early secreted antigenic target 6 kD a are behind the discrepancy around its biological functions
- A new approach based on the serological tests for the diagnosis of tuberculosis in cattle
- Forkhead box O3 (FOXO3) transcription factor mediates apoptosis in BCG-infected macrophages
- Quince (Cydonia oblonga Miller) peel polyphenols modulate LPS-induced inflammation in human THP-1-derived macrophages through NF-κB, p38MAPK and Akt inhibition
- [The macrophage: chief of tuberculosis immune response].
- FOXO3a Transcription Factor mediates Apoptosis of Mycobacterium bovis BCG-Infected Macrophages
- Characterization of a Novel Monoclonal Antibody with Restricted Specificity to the Free β 2 Integrin α M CD11b Subunit
- Use of Taguchi's methods as a basis to optimize hybridoma cell line growth and antibody production in a spinner flask
Publication venues
- Frontiers in Immunology × 5
- International Journal of Molecular Sciences × 1
- RSC Advances × 1
- International Journal of Environmental Health Research × 1
- Analytical Chemistry × 1
- Scientific Reports × 1
Publications per year
- 20262
- 20251
- 20241
- 20231
- 20221
- 20212
- 20193
- 20183
- 20163
- 20153
Collaborations
Partner institutions : Tunis University · Center of Biotechnogy of Borj Cédria · ENSIT · University of Carthage · National Institute of Applied Science and Technology
Co-authors’ countries : France · China · United States · Saudi Arabia
Co-authors
- Meriam Haoues
- Khadija Essafi‐Benkhadir
- Mohamed‐Ridha Barbouche
- Amira Refai
- Habib Karoui
- Ichrak Riahi-Chebbi
- Rania Bouzeyen
- Mohamed Fethi Diouani
- Sonia Ben Hamouda
- Najet Srairi‐Abid
- Houcemeddine Othman
- Ons Zakraoui
Bibliographic data from OpenAlex (open database).
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