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Imen Ghzaiel
Affiliation : Centre National de la Recherche Scientifique · Inserm · Institut Pascal · Université de Bourgogne · Université Clermont Auvergne · Centre de recherche Translationnelle en Médecine moléculaire · Clermont Auvergne INP · Université Bourgogne Europe
- 47Publications (affiliation in France)
- 64Total publications
- 953Citations
- 18h-index
Research profile
Imen Ghzaiel has 47 indexed publications (2016–2026). Their work appears mainly in “Cells”, “Advances in experimental medicine and biology” and “Molecules”. Their most cited article, “Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases” (2022), has been cited 134 times. 14 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in Tunisia, Morocco, Ireland, Lebanon.
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Create my free profile Add my publicationsResearch areas
- Antioxidant Activity and Oxidative Stress
- Plasma Applications and Diagnostics
- Cholesterol and Lipid Metabolism
- Phytochemicals and Antioxidant Activities
- Medicinal Plant Research
Publications (47)
- Synergistic Anticancer Activity of Annona muricata Leaf Extract and Cisplatin in 4T1 Triple-Negative Breast Cancer Cells
- 7-ketocholesterol as a theranostic target: Potential applications and future perspectives
- Erythrocyte trans fatty acid accumulation in elderly sarcopenic patients: biochemical evidence for oxidative stress-driven cis-trans isomerization of membrane lipids
- Oxysterols, age-related-diseases and nutritherapy: Focus on 7-ketocholesterol and 7β-hydroxycholesterol
- Oxysterol-Induced Inflammation in Human Diseases: Strategies for Treatment with Natural Compounds and Synthetic Molecules
- Corrigendum to “Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate” [Curr. Res. Biotechnol. 7 (2024) 100195]
- Implication of cholesterol oxidation products (oxysterols) in neurodegeneration: cytoprotective activities of polyphenols, tocopherols and fatty acids, representative nutrients of the Mediterranean diet
- Natural guardians as radioprotective complements in oncological therapy: A review
- Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health
- Characterization of Silybum marianum and Silybum eburneum seed oils: Phytochemical profiles and antioxidant properties supporting important nutritional interests
- Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue
- Tunisian Silybum Species: Important Sources of Polyphenols, Organic Acids, Minerals, and Proteins across Various Plant Organs
- Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate
- Prevention of Oxysterol-Induced Oxiapoptophagy with Mediterranean Oils: Nutritherapeutic Approach of Age-Related Diseases
- 7β-Hydroxycholesterol and 7-ketocholesterol: New oxidative stress biomarkers of sarcopenia inducing cytotoxic effects on myoblasts and myotubes
- Effects of polyphenols and their metabolites on age-related diseases
- Impact of Oxysterols in Age-Related Disorders and Strategies to Alleviate Adverse Effects
- Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers
- Characterization of Cell Death Induced by Imine Analogs of Trans-Resveratrol: Induction of Mitochondrial Dysfunction and Overproduction of Reactive Oxygen Species Leading to, or Not, Apoptosis without the Increase in the S-Phase of the Cell Cycle
- In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy
- Thymus atlanticus: A Source of Nutrients with Numerous Health Benefits and Important Therapeutic Potential for Age-Related Diseases
- Chemical and Biochemical Features of Spinasterol and Schottenol
- Effects of Cold Plasma on Prostate Cancer Cells: Effet du plasma froid sur les céllules cancéreuses de la prostate
- Saffron (Crocus sativus L.): A Source of Nutrients for Health and for the Treatment of Neuropsychiatric and Age-Related Diseases
- Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications
- Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: Application to age-related diseases and civilization diseases
- Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy
- Role of Bioactive Compounds in the Regulation of Mitochondrial Dysfunctions in Brain and Age-Related Neurodegenerative Diseases
- Role of Diet and Nutrients in SARS-CoV-2 Infection: Incidence on Oxidative Stress, Inflammatory Status and Viral Production
- Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases
- Whole and Purified Aqueous Extracts of Nigella sativa L. Seeds Attenuate Apoptosis and the Overproduction of Reactive Oxygen Species Triggered by p53 Over-Expression in the Yeast Saccharomyces cerevisiae
- Cytotoxic and Antioxidant Activities of Imine Analogs of Trans-Resveratrol towards Murine Neuronal N2a Cells
- Oxiapoptophagy in Age-Related Diseases. Comment on Ouyang et al. 7-Ketocholesterol Induces Oxiapoptophagy and Inhibits Osteogenic Differentiation in MC3T3-E1 Cells. Cells 2022, 11, 2882
- AB1481 RedOx HOMEOSTASIS AND ANTIOXIDANT RESPONSE DEFENSE IN SKELETAL MUSCLE PERFORMANCE IN THE ELDERLY
- List of contributors
- Analysis of the mitochondrial status of murine neuronal N2a cells treated with resveratrol and synthetic isomeric resveratrol analogs: aza-stilbenes
- Oxysterols-induced oxidative stress, mitochondrial and peroxisomal dysfunctions: potential consequences on age-related diseases
- Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases
- 7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19
- Antioxidant Properties and Cytoprotective Effect of Pistacia lentiscus L. Seed Oil against 7β-Hydroxycholesterol-Induced Toxicity in C2C12 Myoblasts: Reduction in Oxidative Stress, Mitochondrial and Peroxisomal Dysfunctions and Attenuation of Cell Death
- Oxysterols and multiple sclerosis: Physiopathology, evolutive biomarkers and therapeutic strategy
- Nigella and Milk Thistle Seed Oils: Potential Cytoprotective Effects against 7β-Hydroxycholesterol-Induced Toxicity on SH-SY5Y Cells
- Association Between Oxidative Stress and Altered Cholesterol Metabolism in Alzheimer’s Disease Patients
- Genetic variants in FADS1 and ELOVL2 increase level of arachidonic acid and the risk of Alzheimer's disease in the Tunisian population
- Evaluation of pro-inflammatory cytokines in frail Tunisian older adults
- AB0027 ARE RHEUMATOID FACTORS AND ANTINUCLEAR ANTIBODIES ASSOCIATED WITH FRAILTY IN ELDERLY TUNISIAN POPULATION?
- The burden of caregivers of patients with Alzheimer's disease
Publication venues
- Cells × 4
- Advances in experimental medicine and biology × 4
- Molecules × 3
- The Journal of Steroid Biochemistry and Molecular Biology × 3
- Nutrients × 3
- Current Research in Biotechnology × 2
Publications per year
- 20263
- 20255
- 20246
- 20239
- 202214
- 20215
- 20203
- 20191
- 20161
Collaborations
Partner institutions : Laboratoire Bio-peroxIL · University of Monastir · Tunis El Manar University · Université Bourgogne Franche-Comté · University of Sousse
Co-authors’ countries : Tunisia · Morocco · Ireland · Lebanon
Co-authors
- Gérard Lizard
- Anne Véjux
- Thomas Nury
- Mohamed Ksila
- Mohammad Hadi Samadi
- Norbert Latruffe
- Vivien Pires
- Aline Yammine
- Dominique Fasseur
- Khouloud Sassi
- P. Jouanny
- Soukaina Essadek
Bibliographic data from OpenAlex (open database).
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