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Kephas Otieno
Affiliation : Kenya Medical Research Institute · Centers for Disease Control and Prevention
- 52Publications (affiliation in Kenya)
Research profile
Kephas Otieno has 52 indexed publications (2006–2026). Their work appears mainly in “Malaria Journal”, “Clinical Infectious Diseases” and “The Lancet”. Their most cited article, “Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine” (2015), has been cited 423 times. 11 of these publications date from the last three years of activity. Their work is co-authored with at least 12 researchers, including institutions in United States, United Kingdom, Spain, Uganda.
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Create my free profile Add my publicationsPublications (52)
- Continental-scale genomic surveillance of Plasmodium falciparum malaria across sub-Saharan Africa with rapid nanopore sequencing
- The burden of malaria-attributable maternal anaemia and the impact of preventive treatment across sub-Saharan Africa
- Safety and efficacy of the monoclonal antibody L9LS for malaria prevention in children exposed to perennial malaria transmission in Kenya: a randomised, double-blind, placebo-controlled, phase 2 trial
- Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya) – Effect of ATSBs on epidemiologic and entomologic indicators: A Phase III, open-label, cluster-randomised, controlled trial
- Investigating the Role of Cytomegalovirus as a Cause of Stillbirths and Child Deaths in Low- and Middle-Income Countries Through Postmortem Minimally Invasive Tissue Sampling
- Sustained efficacy of the RTS,S/AS01E malaria vaccine over 50 months of follow-up when used in full-dose or fractional-dose regimens in young children in Ghana and Kenya: final results from an open-label, phase 2b, randomised controlled trial
- Burden of child mortality from malaria in high endemic areas: Results from the CHAMPS network using minimally invasive tissue sampling
- Chemoprevention for malaria with monthly intermittent preventive treatment with dihydroartemisinin–piperaquine in pregnant women living with HIV on daily co-trimoxazole in Kenya and Malawi: a randomised, double-blind, placebo-controlled trial
- Genotypic analysis of RTS,S/AS01E malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5–17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial
- Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine
- Could Less Be More? Accounting for Fractional-Dose Regimens and Different Number of Vaccine Doses When Measuring the Impact of the RTS,S/AS01E Malaria Vaccine
- Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine–pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial
- A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa
- Public-private partnership to rapidly strengthen and scale COVID-19 response in Western Kenya
- Efficacy of RTS,S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial
- Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria among Children in Western Kenya, 2016 to 2017
- Diagnostic Performance of Loop-Mediated Isothermal Amplification and Ultrasensitive Rapid Diagnostic Tests for Malaria Screening Among Pregnant Women in Kenya
- Temporal trends in molecular markers of drug resistance in Plasmodium falciparum in human blood and profiles of corresponding resistant markers in mosquito oocysts in Asembo, western Kenya
- Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial
- Intermittent screening and treatment with artemisinin-combination therapy versus intermittent preventive treatment with sulphadoxine-pyrimethamine for malaria in pregnancy: a systematic review and individual participant data meta-analysis of randomised clinical trials
- Performance of a rapid antigen test for SARS-CoV-2 in Kenya
- Malaria Chemoprevention in the Postdischarge Management of Severe Anemia
- Impact of Community-Based Mass Testing and Treatment on Malaria Infection Prevalence in a High-Transmission Area of Western Kenya: A Cluster Randomized Controlled Trial
- Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efficacy study in western Kenya
- Impact of Intermittent Mass Testing and Treatment on Incidence of Malaria Infection in a High Transmission Area of Western Kenya
- Evaluation of the colorimetric malachite green loop-mediated isothermal amplification (MG-LAMP) assay for the detection of malaria species at two different health facilities in a malaria endemic area of western Kenya
- Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy
- Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
- Safety, Tolerability, and Immunogenicity of Plasmodium falciparum Sporozoite Vaccine Administered by Direct Venous Inoculation to Infants and Young Children: Findings From an Age De-escalation, Dose-Escalation, Double-blind, Randomized Controlled Study in Western Kenya
- Modelling the relationship between malaria prevalence as a measure of transmission and mortality across age groups
- Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned
- Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections
- Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012
- Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial
- Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya
- Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
- Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial
- Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin–piperaquine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for the control of malaria during pregnancy in western Kenya: an open-label, three-group, randomised controlled superiority trial
- Impact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight
- Emergence of Community-Acquired, Multidrug-Resistant Invasive NontyphoidalSalmonellaDisease in Rural Western Kenya, 2009–2013
- Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya
- Intermittent Preventive Treatment of Malaria in Pregnancy with Mefloquine in HIV-Infected Women Receiving Cotrimoxazole Prophylaxis: A Multicenter Randomized Placebo-Controlled Trial
- Serological markers for monitoring historical changes in malaria transmission intensity in a highly endemic region of Western Kenya, 1994–2009
- A Quality Control Program within a Clinical Trial Consortium for PCR Protocols To Detect Plasmodium Species
- A randomized trial of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated malaria among children in western Kenya
- Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya
- Performance of Malaria Rapid Diagnostic Tests as Part of Routine Malaria Case Management in Kenya
- In‐vivo efficacy of amodiaquine‐artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya
- Does Cotrimoxazole Prophylaxis for the Prevention of HIV-Associated Opportunistic Infections Select for Resistant Pathogens in Kenyan Adults?
- Plasma Folate Level and High‐Dose Folate Supplementation Predict Sulfadoxine‐Pyrimethamine Treatment Failure in Pregnant Women in Western Kenya Who Have Uncomplicated Malaria
- Malaria and anaemia among pregnant women at first antenatal clinic visit in Kisumu, western Kenya
- A Randomized Controlled Trial of Folate Supplementation When Treating Malaria in Pregnancy with Sulfadoxine-Pyrimethamine
Publication venues
- Malaria Journal × 11
- Clinical Infectious Diseases × 5
- The Lancet × 4
- The Lancet Infectious Diseases × 4
- Nature Communications × 3
- The Journal of Infectious Diseases × 3
Publications per year
- 20263
- 20253
- 20245
- 20233
- 20224
- 20213
- 20206
- 20194
- 20181
- 20163
Collaborations
Partner institutions : Division of Parasitic Diseases and Malaria · Liverpool School of Tropical Medicine · Center for Global Health · University of Liverpool · Atlanta Research and Education Foundation
Co-authors’ countries : United States · United Kingdom · Spain · Uganda
Co-authors
- Simon Kariuki
- Aaron M. Samuels
- Peter Ouma
- Martina Oneko
- Chris Odero
- Mary J. Hamel
- Tony Sang
- Vincent Omondi Were
- Meghna R. Desai
- Walter Otieno
- Feiko O. ter Kuile
- Dennis K Bii
Bibliographic data from OpenAlex (open database).
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