Accueil › Annuaire des chercheurs › Kephas Otieno
Kephas Otieno
Affiliation : Kenya Medical Research Institute · Centers for Disease Control and Prevention
- 52Publications (affiliation kényane)
Profil de recherche
Kephas Otieno compte 52 publications référencées (2006–2026). Ses travaux paraissent principalement dans « Malaria Journal », « Clinical Infectious Diseases » et « The Lancet ». Son article le plus cité, « Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine » (2015), a été cité 423 fois. 11 de ces publications datent des trois dernières années d’activité. Ses travaux sont cosignés avec au moins 12 chercheurs, notamment dans des établissements de États-Unis, Royaume-Uni, Espagne, Ouganda.
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- Continental-scale genomic surveillance of Plasmodium falciparum malaria across sub-Saharan Africa with rapid nanopore sequencing
- The burden of malaria-attributable maternal anaemia and the impact of preventive treatment across sub-Saharan Africa
- Safety and efficacy of the monoclonal antibody L9LS for malaria prevention in children exposed to perennial malaria transmission in Kenya: a randomised, double-blind, placebo-controlled, phase 2 trial
- Attractive targeted sugar baits for malaria control in western Kenya (ATSB-Kenya) – Effect of ATSBs on epidemiologic and entomologic indicators: A Phase III, open-label, cluster-randomised, controlled trial
- Investigating the Role of Cytomegalovirus as a Cause of Stillbirths and Child Deaths in Low- and Middle-Income Countries Through Postmortem Minimally Invasive Tissue Sampling
- Sustained efficacy of the RTS,S/AS01E malaria vaccine over 50 months of follow-up when used in full-dose or fractional-dose regimens in young children in Ghana and Kenya: final results from an open-label, phase 2b, randomised controlled trial
- Burden of child mortality from malaria in high endemic areas: Results from the CHAMPS network using minimally invasive tissue sampling
- Chemoprevention for malaria with monthly intermittent preventive treatment with dihydroartemisinin–piperaquine in pregnant women living with HIV on daily co-trimoxazole in Kenya and Malawi: a randomised, double-blind, placebo-controlled trial
- Genotypic analysis of RTS,S/AS01E malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5–17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial
- Innate immune activation restricts priming and protective efficacy of the radiation-attenuated PfSPZ malaria vaccine
- Could Less Be More? Accounting for Fractional-Dose Regimens and Different Number of Vaccine Doses When Measuring the Impact of the RTS,S/AS01E Malaria Vaccine
- Effect of monthly intermittent preventive treatment with dihydroartemisinin–piperaquine with and without azithromycin versus monthly sulfadoxine–pyrimethamine on adverse pregnancy outcomes in Africa: a double-blind randomised, partly placebo-controlled trial
- A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa
- Public-private partnership to rapidly strengthen and scale COVID-19 response in Western Kenya
- Efficacy of RTS,S/AS01E malaria vaccine administered according to different full, fractional, and delayed third or early fourth dose regimens in children aged 5–17 months in Ghana and Kenya: an open-label, phase 2b, randomised controlled trial
- Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria among Children in Western Kenya, 2016 to 2017
- Diagnostic Performance of Loop-Mediated Isothermal Amplification and Ultrasensitive Rapid Diagnostic Tests for Malaria Screening Among Pregnant Women in Kenya
- Temporal trends in molecular markers of drug resistance in Plasmodium falciparum in human blood and profiles of corresponding resistant markers in mosquito oocysts in Asembo, western Kenya
- Safety, immunogenicity and efficacy of PfSPZ Vaccine against malaria in infants in western Kenya: a double-blind, randomized, placebo-controlled phase 2 trial
- Intermittent screening and treatment with artemisinin-combination therapy versus intermittent preventive treatment with sulphadoxine-pyrimethamine for malaria in pregnancy: a systematic review and individual participant data meta-analysis of randomised clinical trials
- Performance of a rapid antigen test for SARS-CoV-2 in Kenya
- Malaria Chemoprevention in the Postdischarge Management of Severe Anemia
- Impact of Community-Based Mass Testing and Treatment on Malaria Infection Prevalence in a High-Transmission Area of Western Kenya: A Cluster Randomized Controlled Trial
- Assessment of molecular markers of anti-malarial drug resistance among children participating in a therapeutic efficacy study in western Kenya
- Impact of Intermittent Mass Testing and Treatment on Incidence of Malaria Infection in a High Transmission Area of Western Kenya
- Evaluation of the colorimetric malachite green loop-mediated isothermal amplification (MG-LAMP) assay for the detection of malaria species at two different health facilities in a malaria endemic area of western Kenya
- Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy
- Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa
- Safety, Tolerability, and Immunogenicity of Plasmodium falciparum Sporozoite Vaccine Administered by Direct Venous Inoculation to Infants and Young Children: Findings From an Age De-escalation, Dose-Escalation, Double-blind, Randomized Controlled Study in Western Kenya
- Modelling the relationship between malaria prevalence as a measure of transmission and mortality across age groups
- Community-based intermittent mass testing and treatment for malaria in an area of high transmission intensity, western Kenya: development of study site infrastructure and lessons learned
- Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections
- Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012
- Safety and immunogenicity of RTS,S/AS01 malaria vaccine in infants and children with WHO stage 1 or 2 HIV disease: a randomised, double-blind, controlled trial
- Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya
- Genetic Diversity and Protective Efficacy of the RTS,S/AS01 Malaria Vaccine
- Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial
- Intermittent screening and treatment or intermittent preventive treatment with dihydroartemisinin–piperaquine versus intermittent preventive treatment with sulfadoxine–pyrimethamine for the control of malaria during pregnancy in western Kenya: an open-label, three-group, randomised controlled superiority trial
- Impact of Sulfadoxine-Pyrimethamine Resistance on Effectiveness of Intermittent Preventive Therapy for Malaria in Pregnancy at Clearing Infections and Preventing Low Birth Weight
- Emergence of Community-Acquired, Multidrug-Resistant Invasive NontyphoidalSalmonellaDisease in Rural Western Kenya, 2009–2013
- Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya
- Intermittent Preventive Treatment of Malaria in Pregnancy with Mefloquine in HIV-Infected Women Receiving Cotrimoxazole Prophylaxis: A Multicenter Randomized Placebo-Controlled Trial
- Serological markers for monitoring historical changes in malaria transmission intensity in a highly endemic region of Western Kenya, 1994–2009
- A Quality Control Program within a Clinical Trial Consortium for PCR Protocols To Detect Plasmodium Species
- A randomized trial of artemether-lumefantrine and dihydroartemisinin-piperaquine in the treatment of uncomplicated malaria among children in western Kenya
- Temporal trends of sulphadoxine-pyrimethamine (SP) drug-resistance molecular markers in Plasmodium falciparum parasites from pregnant women in western Kenya
- Performance of Malaria Rapid Diagnostic Tests as Part of Routine Malaria Case Management in Kenya
- In‐vivo efficacy of amodiaquine‐artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya
- Does Cotrimoxazole Prophylaxis for the Prevention of HIV-Associated Opportunistic Infections Select for Resistant Pathogens in Kenyan Adults?
- Plasma Folate Level and High‐Dose Folate Supplementation Predict Sulfadoxine‐Pyrimethamine Treatment Failure in Pregnant Women in Western Kenya Who Have Uncomplicated Malaria
- Malaria and anaemia among pregnant women at first antenatal clinic visit in Kisumu, western Kenya
- A Randomized Controlled Trial of Folate Supplementation When Treating Malaria in Pregnancy with Sulfadoxine-Pyrimethamine
Revues de publication
- Malaria Journal × 11
- Clinical Infectious Diseases × 5
- The Lancet × 4
- The Lancet Infectious Diseases × 4
- Nature Communications × 3
- The Journal of Infectious Diseases × 3
Publications par année
- 20263
- 20253
- 20245
- 20233
- 20224
- 20213
- 20206
- 20194
- 20181
- 20163
Collaborations
Établissements partenaires : Division of Parasitic Diseases and Malaria · Liverpool School of Tropical Medicine · Center for Global Health · University of Liverpool · Atlanta Research and Education Foundation
Pays des co-auteurs : États-Unis · Royaume-Uni · Espagne · Ouganda
Co-auteurs
- Simon Kariuki
- Aaron M. Samuels
- Peter Ouma
- Martina Oneko
- Chris Odero
- Mary J. Hamel
- Tony Sang
- Vincent Omondi Were
- Meghna R. Desai
- Walter Otieno
- Feiko O. ter Kuile
- Dennis K Bii
Données bibliographiques issues d’OpenAlex (base ouverte).
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